satoru.bio  ·  DigiShield Labs

Satoru

悟る — to perceive, to awaken to understanding

Satoru uses large language models to extract and synthesise fragmented biological knowledge at scale — making decades of specialised research queryable and accessible for the first time. We begin where data is richest and most opaque: deep time.

SMILE Phase One Complete

Systematic Microbiome Intelligence for Lost Ecosystems

The first comprehensive, queryable database of prehistoric oral microbiomes, aggregating ancient samples from published literature into a standardised, spatially-indexed corpus with authentication metadata. SMILE makes cross-study comparative research tractable for the first time — resolving the metadata fragmentation that has blocked systematic analysis of human-microbe co-evolution across deep time.

1,414
Oral samples
16,196
Microbiome records
45
Publications
~49,000
Year span (BP)
PostGIS
Spatial index
~49,000 BP · Neanderthal Medieval Europe
Ancient Resistome In Development

Antibiotic Resistance Gene Database · Deep Time

The first unified database of antibiotic resistance genes recovered from ancient biological material — establishing a pre-antibiotic baseline for AMR evolution research across deep time.

AI-Powered Extraction

A tiered large language model pipeline processes scientific publications through sequential classification, sample reconciliation, taxonomic composition extraction, authentication scoring, and methodological metadata capture. Model selection is calibrated to task complexity; quality is validated against known ground-truth datasets.

Domain Expertise as Ground Truth

Satoru is built and validated by a specialist in bioarchaeological data. The principal investigator holds a PhD in Archaeology specialising in stable isotope analysis and organic residue analysis — providing direct disciplinary authority to assess and correct extraction outputs.

Open Science

All aggregated databases are freely accessible under CC-BY 4.0 licensing. Extraction methodology will be published for peer review and community replication. The infrastructure is designed to be extended, forked, and adapted across biological domains beyond the initial scope.

Spatial Infrastructure

PostgreSQL 16 with PostGIS enables geographic and temporal queries across the corpus — supporting regional comparisons, site-level drill-downs, and spatiotemporal visualisation. Each sample is georeferenced at point level with SRID 4326 and linked to archival sequence accessions where available.

Collaborate or Inquire

Academic partnerships, data access, and grant enquiries welcome.